In their own words:
As we have already discussed on this blog, 1) the vaccine doesn’t do shit to prevent infection or transmission and 2) this was predictable from the beginning if you know anything about the evolution of pathogens. In a mass-vaxxed population, each successive “wave” (i.e., each selective sweep) will be less affected by the vaccine than the one before. This fact is demonstrated clearly by this paper by Wang, Chen and Wei from Michigan State University*, which shows a clear thermodynamic difference between detected mutations in SARS-COV-2 spike protein that allows most of them to be split into “competition specialists” with greater affinity for the human ACE-2 receptor, or “defense specialists” that have weaker affinity for vaccine-induced antibodies. (Note that the dichotomy of competition vs. defense is my own addition, based on the Red Queen hypothesis and the “Kill-the-winner” theory of viral evolution.) Wang et al. demonstrate that the vaccine-resistant defense mutations, such as the one that defined the Delta variant, only spread efficiently in populations after mass vaccination began. Presumably the new “Omicron” variant represents an even greater level of resistance, or else it would not be able to displace Delta. Presumably also, neither Delta nor Omicron would be as successful in a predominantly unvaccinated population due to trade-offs between antibody resistance and ACE-2 affinity (although Wang et al also demonstrate the amazing power of viral evolution, in that the defense mutations are almost always found in combination with one or more competition mutations, presumably all convergently evolved unless we have way more COVID-19 superinfections occurring than one would expect).
Which is to say, of course, that viral evolution is rendering whatever immunity was originally conferred by the COVID vaccines increasingly irrelevant. We are told that boosters are effective, but it’s not clear to me why this should be, since they only reactivate the same memory B-cells that infection would reactivate. Perhaps having a large number of currently circulating antibodies provides some relief from symptoms by compensating for the reduced antibody affinity for the virus? But if that’s the case, how long can that possibly last? And if every shot carries with it the risk of heart issues — caused, I imagine, by cardiac tissue expressing SARS-COV-2 spike mRNA and eliciting autoimmune attacks by the well-trained adaptive immune system — then surely we are moving into a period where the risk of maintaining a constant immune response outweighs whatever tiny risk the virus carries? The immune system attacks viruses by destroying human cells. Chronic high-level immune activity leads to chronic inflammation, which over the long run causes all sorts of problems. Moreover, if simply upping the dose of antibodies hugely above the natural response is effective at reducing symptoms, is not post-infection monoclonal antibody treatment not exactly equivalent in mechanism to the effect of boosters, only with the advantages of 1) avoiding chronic immune response, 2) avoiding expression of spike protein in non-respiratory circulatory tissue, and 3) more readily allowing updates to the antibodies used for treatment to track the evolution of the virus?
Instead, health authorities throughout western civilization appear to be doubling-down on vaccination, even as the vaccines lose any possible theoretical justification. The US government, and its lackies throughout the Cathedral (including, of course, my employers, as well as those of Wang et al and thousands of other scientists who are still capable of critical thinking) are willing to shutter businesses and cast western civilization’s brightest talents into the outer darkness to bolster a vaccine that doesn’t work. However bad COVID-19 might be, it’s nowhere near as bad as being poor. Why, then, do they push so hard in support of this crap drug? My suspicion is that it’s equal parts malevolence and incompetence, propped up by a servile population that has swallowed all the hysterical propaganda they’ve been fed over the past two years to the point they’ll do anything they irrationally believe will protect them.
Will 2022 be any better than 2021? My guess is no, it’s an election year, and the government will double down on its fear porn and its outright repression of dissent as a mechanism to keep from losing power. The COVID-19 pandemic is clearly over; all that we are left with is a pandemic of government. What is the vaccine for that? Show me, and I’ll happily take as many booster doses as you want to give me.
* Michigan State University, where I spent 4.5 years of my life studying microbial evolution, has embarrassingly become a bastion of the anti-science left. It is a sad state of affairs that this paper had to come from MSU’s math and engineering departments, with no input from MSU’s formerly world-class microbiology and/or EEB departments. Remember kids — woke, not even once.